About forty pages of new matter have been added, but the book is no larger than before, as a corresponding number of pages have been omitted from the bibliography. A complete bibliography of the subject would now need a separate volume, and it has therefore seemed best to omit all but the most important references.The principal additions to the book include an account of Professor Oliver's tintometer and hæmoglobinometer (which are the only new instruments of importance), new matter in the chapter on the primary anæmias, and on leukæmia, and a description of Müller's blood-dust (the newly discovered constituent of normal and abnormal blood). Bremer's and Williamson's tests for diabetic blood and the iodine reaction in the blood during acute surpurative processes are described, and blood exminations are recorded in Malta fever, yellow fever, epidemic dropsy, beri-beri, relapsing fever, tetanus, chickenpox, whooping-cough, and epidemic cerebro-spinal meningitis, diseases not included in previous editions. New observations on poisoning by alcohol, opium, corrosives, and ptomains, on aneurisms, on paroxysmal hæmoglobinaemia, and on cretinism are recorded.I have wished to draw especial attention to the tendency to an oval or sausage shape among the red corpuscles in cases of grave anæmia and to the occurrence of adventitious forms of leucocytes in leucocytosis.Some of my critics have regretted that there was so little theoretical discussion in the book. In this edition I have for the most part eliminated what little there was before. It had already become out of date.
Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail, along with their characterization aspects and effects of their dimensions on drug delivery systems behavior in-vitro and in-vivo. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/genes for enhanced clinical efficacy. Provides the present state of widely used lipid-based nanoparticulate delivery systemsExplores how lipid-based nanocarriers improve drug delivery safetyDescribes the nanoformulation design and the preparation methods of lipid-based nanocarriers
Patellofemoral complaints are a major problem for all those working in sports medicine and orthopaedics. The correct diagnosis at an early stage is essential if subsequent treatment is to be successful and secondary complications are to be avoided. Written by an internationally known team of experts this book looks at the various diagnostic techniques currently available, cites examples of unsuccessful treatments and proposes the most appropriate ones on the proven basis of the latest research. The core of the book is the 20 case studies ranging from simple non-operative treatment to multi-operated patients with salvage procedures. The underlying theme of the book is that treatment of patellofemoral problems must, in the first instance, be somewhat conservative. Surgical interventions should be performed in a response to a clear underlying pathology and only after non-operative treatment has failed. Patellofemoral Disorders is enhanced by the inclusion of some superb specially drawn illustrations and numerous colour photographs in the case studies section.
While diabetes can usually be well-controlled using modern therapies, metabolic emergencies inevitably occur. This book provides an easy-to-read yet comprehensive account of emergencies in diabetes conveniently collected into one volume. For each topic, a brief review of the pathophysiology is followed by a description of cardinal clinical features, clinical and biochemical assessment and clinical management. * Clear, informative text for rapid and easy assimilation * Emphasis on evidence-based medicine * Effective use of illustrations to highlight and summarize key points Designed to fit conveniently into the pocket of a white coat, this book should be readily to hand in all hospital medical wards, particularly A&E. It will be useful to junior hospital doctors across a wide range of specialties, senior house officers in general medical training, and nurses involved in the care of patients with diabetes.
Recent developments within molecular biology and genetic engineering have led to huge advances and changes within the biological sciences especially within the field of human genetics. Diagnostic Techniques in Genetics offers an important overview of how DNA or RNA technology may be applied to a large set of genetic diagnoses. The first part of the book focuses on DNA/RNA applications and includes many of the latest developments in the field combined with routine procedures of genetic diagnoses, for example cloning and sequencing DNA. The DNA applications presented in the first chapter are then each applied to a specific kind of genetic diagnosis and the text concludes with a chapter devoted to population genetics. First published in French by Dunod in 2002, this book is an excellent reference for students taking courses in molecular biology, medicine and medical genetics. It is also a useful introduction for postgraduate students and researchers in the field who require a general overview of genetic diagnoses.
Poultry Coccidiosis is a valuable, comprehensive reference that reviews the biology of coccidia, covers current diagnostic and testing procedures, and thoroughly covers the anti-coccidial vaccines and drugs that are currently available. This user-friendly guide will provide poultry scientists, poultry disease diagnosticians, and veterinary practitioners with a well-illustrated description of the Johnson and Reid scoring procedure, thorough explanation of laboratory procedures, experiment design, example protocols for testing anticoccidial drugs, a summary of the chemical name, structure, safety, and efficacy of anticoccidial drugs, and a review of anticoccidial vaccines that are currently available. This easy-to-use reference will be an invaluable tool for anyone working with poultry.
How can prenatal testing help your patients? In utero diagnosis has undergone an amazing revolution in recent years. More tests are available; the indications for prenatal diagnosis have expanded - you can now advise your patients about disorders you could not have previously detected. Medical training for obstetricians, medical geneticists, and genetic counselors has not kept pace with these developments. Clinical exposure to common and unusual problems in prenatal diagnosis is limited. Prenatal Diagnosis: Clinical Cases and Challenges, based on the authors’ several decades of experiences, fills this gap. Real cases portray diagnostic problems as a route to the underlying biology, the available testing options, and the results that might be obtained. The authors discuss the challenges of management, interpretation, and counseling. Cases used throughout emphasize three types of clinical problems: Chromosomal abnormalities Mendelian disorders Fetal structural abnormalities The decision to enter the world of prenatal diagnosis should be very carefully considered by any prospective mother. Prenatal Diagnosis: Clinical Cases and Challenges will help you discuss the issues in an informed manner with your patients.
In recent years cellular pathology has become more closely involved in the direct management of patients with the introduction of molecular technologies and targeted therapies. Advanced Techniques in Diagnostic Cellular Pathology introduces students and professionals to these concepts and the key technologies that are influencing clinical practice today. Each chapter is carefully structured to introduce the very latest techniques and describe their clinical purpose, principle, method and application in cellular pathology. The advantages of various methods for preparing, observing and demonstrating cells and tissues employed to assist in diagnosis are explored, in addition to the use of quantitative methods in the detection and diagnosis of disease. Supplementary web-based material including annotated virtual microscope slides is available with the book. This is provided courtesy of i-Path Diagnostics Ltd and can be accessed online from their website www.pathxl.com Describes the very latest, emerging and established molecular aspects of diagnostic pathology. A clear, focused approach with each chapter containing a summary, a review of basic principles and clinical applications. Includes web-based annotated virtual microscope slides. Contributions from experienced practitioners contain numerous real-world examples illustrating the use of different diagnostic techniques, and their clinical relevance Written by a team of experienced practitioners this book will prove invaluable both to postgraduate biomedical science students who are training to be cellular pathologists and to professionals working in diagnostic and research laboratories as part of their continuing professional development.
This unique book is written by Barbara Bain, a leading haematologist with a reputation for her educational prowess in the field. It provides a concise overview of the haemoglobinopathies and focuses on the selection, performance, and interpretation of relevant laboratory tests. The tests dealt with are mainly those done regularly in diagnostic haematology laboratories. Where more specialist tests are required, the reader is given an overview of what the specialist centre will do, with guidance on what the result will imply. This book is extremely practical in orientation and is an essential reference volume in the haematology laboratory. Haemoglobinopathy Diagnosis is ideal for: Trainees and residents in haematology Hematologists in practice Laboratory scientists Why Buy This Book? New Edition - Fully updated, with 43 new pictures and 37 pages of illustrated clinical cases to use for teaching and self-evaluation Essential reference volume for the haematology laboratory Focuses on diagnosis Very practical in its approach In addition to the self-assessment case studies, contains "test your knowledge" sections at the end of every chapter Remarkably comprehensive for a compact book
Stroke is a major cause of morbidity and mortality, with carotid disease representing an important contributory risk factor. This book is about the pathogenesis and management of carotid disease with specific focus on the role imaging has to play in the early recognition of symptomatic and asymptomatic disease as well as the treatment of the developed condition. Technological advances in imaging modalities now allow detailed analysis of the disease progression, the prediction of critical events leading to a stroke, as well as the identification of the most effective surgical or other interventional treatments. This book should be read by neurologists, cardiologists, vascular surgeons, neurosurgeons and radiologists involved in the care of patients with carotid disease, and also by researchers involved in the development of new therapeutic techniques and drugs.
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