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Monoclonal Antibodies -- Principles and Practice

单克隆抗体：原理与实践

ISBN：9780122870231，出版年：1996，中图分类号：R3

Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology. The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies. The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference. This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use.Provides an integrated treatment of both the production and application of monoclonals in cell biology, biochemistry, and immunologyGives detailed and critical accounts of the theory, production, purification, storage, and relabelling of monoclonals, and their use in antigen characterization, affinity chromorography, and immunofluroscenceComprehensively updated to cover the rapid advances that have occurred since the publication of the Second Edition

Precautionary principle Principle of indifference One-shot deviation principle Indium antimonide Preventive ethics Guiding Principles First Principles of Instruction Anthropic principle Superposition principle Ethical practice

Nanotoxicity -- Prevention and Antibacterial Applications of Nanomaterials

纳米材料的纳米毒性预防和抗菌应用

Elsevier Science_RM

ISBN：9780128199435，出版年：2020，中图分类号：TB3

Nanotoxicity: Prevention, and Antibacterial Applications of Nanomaterials focuses on the fundamental concepts for cytotoxicity and genotoxicity of nanomaterials. It sheds more light on the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media. The book provides good guidance for toxic prevention methods and management in the manufacture/application/disposal. The book also discusses the potential applications of nanomaterials-based antibiotics. The potential toxic effects of nanomaterials result not only from the type of base materials, but also from their size/ ligands/surface chemical modifications. This book discusses why different classes of nanomaterials display toxic properties, and what can be done to mitigate this toxicity. It also explores how nanomaterials are being used as antimicrobial agents, being used to purify air and water, and counteract a range of infectious diseases. This is an important reference for materials scientists, environmental scientists and biomedical scientists, who are seeking to gain a greater understanding of how nanomaterials can be used to combat toxic agents, and how the toxicity of nanomaterials themselves can best be mitigated.Explains the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological mediaOutlines major methods for mitigating and prevention of nanotoxicityDiscusses the applications of nanomaterials-based antibiotics

Theranostic Nanomedicine Indium antimonide Immunocytochemistry Antibiotics Anti-angiogenic drugs Anti angiogenic Anticholinesterase poisoning Antireticular cytotoxic serum Proteotoxicity Immunohistochemistry