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Tissue Engineering of Temporomandibular Joint Cartilage

颞下颌关节软骨组织工程

Morgan & Claypool Publishers Athanasiou, Kyriacos Almarza, Alejandro J Detamore, Michael S

ISBN：9781598299960，出版年：2009，中图分类号：R3

The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of this unusual joint. Damage or disease to these tissues significantly impacts a patient's quality of life by making common activities such as talking and eating difficult and painful. Unfortunately, these tissues have limited ability to heal, necessitating the development of treatments for repair or replacement. The burgeoning field of tissue engineering holds promise that replacement tissues can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical, biochemical, and anatomical characteristics of the disc and condylar cartilage, and also provides a historical perspective of past and current TMJ treatments and previous tissue engineering efforts. This book was written to serve as a reference for researchers seeking to learn about the TMJ, for undergraduate and graduate level courses, and as a compendium of TMJ tissue engineering design criteria. Table of Contents: The Temporomandibular Joint / Fibrocartilage of the TMJ Disc / Cartilage of the Mandibular Condyle / Tissue Engineering of the Disc / Tissue Engineering of the Mandibular Condyle / Current Perspectives

Cartilage tissue engineering Bone tissue engineering Cartilaginous Tissue Tissue engineering Synthetic bone graft Cartilage tissues Skeletal tissue Periodontal tissue Synthetic bone Bone tissue

Joint and Muscle Dysfunction of the Temporomandibular Joint -- Special Topic Issue: Cells Tissues Organs 2003, Vol. 174, No. 1-2

颞下颌关节的关节和肌肉功能障碍

S.Karger

ISBN：9783805575980，出版年：2003，中图分类号：R6

Temporomandibular (jaw) joint diseases and disorders are estimated to affect 10 million Americans every year with the majority of those seeking treatment being women in their childbearing years. Researchers generally agree that the most common temporomandibular diseases and disorders fall into three main categories: arthritis, internal derangement of the joint, and/or myofascial pain. This special issue of Cells Tissues Organs is a selection of papers presented at the second meeting of the Temporomandibular Joint Association held in May 2002. The meeting focused on the role that osteoarthritis and muscle mechanics play in temporomandibular joint diseases and disorders. Currently there are no established treatments for temporomandibular joint conditions, so that the therapies patients receive generally reflect the personal views and practices of the provider. These papers will serve as a reference for clinical and basic research in this field, as well as a stimulus for future investigations. Clinicians dealing with chronic musculoskeletal disorders such as arthritis will benefit by expanding their perspective to include new knowledge about their fields as well as about similar disorders of the head and neck. Basic and translational researchers in the same fields should read these papers because we hope that this will encourage them to evaluate both the unique and the generalized features of research related to temporomandibular disorders.

Muscle Cell Contraction Muscle tissue Semimembranosus muscle Multi organ dysfunction Neuronal cell body Cell contractility Bone tissue Skeletal muscle fibrosis Cellular cation homeostasis Periodontal tissue