Part I. J. B. S. Haldane: 1. Haldane's ideas in biology with special reference to disease and evolution James F. Crow 2. JBS Haldane and the malaria hypothesis D. J. Weatherall Part II. malarial parasites: 3. Evolutionary genetics of Plasmodium Falciparum, the agent of malignant malaria Stephen M. Rich and Francisco J. Ayala 4. Evolutionary biology of malaria parasites Ananias A. Escalante and Altaf A. Lal 5. G6PD deficiency and malarial resistance in humans: insights from evolutionary genetic analyses Sara A. Tishkoff and Brian C. Verrelli 6. The enigma of vivax malaria and erythrocyte duffy-negativity Peter A. Zimmerman Part III. Other Parasites: 7. Influenza evolution Robin M. Bush and Nancy J. Cox 8. Free-living to free-wheeling: the evolution of Vibrio cholerae from innocence to infamy Rita R. Colwell, Shah M. Faruque and G. Balakrish Nair 9. Evolutionary dynamics of Daphnia and their microparasites Tom Little and Dieter Ebert 10. Human susceptibility to visceral Leishmaniasis (Leishmania donovani) and to Schistosomiasis (Schistosoma mansoni) is controlled by major genetic loci A. Dessein, B. Bucheton, L. Argiro, N. M. A. Elwali, V. Rodrigues, C. Chevillard, S. Marquet, Helia Dessein, S. H. El-Safi and L. Abel Part IV. Genetic and Evolutionary Considerations: 11. The evolution of pathogen virulence in response to animal and public health interventions Andrew F. Read, Sylvain Gandon, Sean Nee and Margaret J. Mackinnon 12. Infection and the diversity of regulatory DNA Lindsay G. Cowell, N. Avrion Mitchison and Brigitte Muller 13. Genetic epidemiology of infectious diseases: the first half century Newton E. Morton 14. The impact of human genetic diversity in the transmission and severity of infectious diseases Michel Tibayrenc 15. Evolution and the etiology of diabetes mellitus Kyle D. Cochran and Gregory M. Cochran 16. The future of human evolution Luca Cavalli-Sforza.
The biological wealth of our planet is represented by the biodiversity that surrounds us. Our future wellbeing depends on the care and conservation that we practice to protect and enhance that biodiversity, which resides mostly in developing countries. Yet, the holders of traditional knowledge remain poor, while those exploiting it commercially become prosperous. As we utilize recombinant DNA technology to achieve food security and other goals, serious apprehension has arisen in the public mind with regard to the impact of genetically modified crops on our environment and health. Similarly, the long-term impact of gene therapy is not known either. These dilemmas and their ethical implications are examined in this book in the context of intellectual property rights and international cooperation.
With a foreword by S ZuckermanThe First Julian Huxley Memorial Lecture by J NeedhamSir Julian Huxley was especially noted for his versatility — great biologist, first Director-General of UNESCO, Director of the London Zoo, bird watcher, skilled popular writer of science and a tireless champion of wildlife conservation. This book is a biographical account of Huxley as revealed through his own correspondence and the correspondence of his great contemporaries. An introductory biographical summary is followed by his and others' letters and a collection of some of his writings. A complete bibliography of Huxley is included. The book would be of great interest to all biologists, students of the United Nations, historians of science and nature conservationists.
The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, its applications have also resulted in some undesirable consequences such as diminished species biodiversity as well as diminished agrobiodiversity, environmental contamination, and the exploitation of intellectual property rights and patents in appropriating the biodiversity of developing countries.This book discusses the role of biological, ecological, environmental, ethical, and economic issues in the interaction between biotechnology and biodiversity, using different contexts. No other book has discussed all of these issues in a comprehensive manner. Of special interest is their impact when biotechnology is shared between developed and developing countries, and the lack of recognition of the rights of indigenous populations and traditional farmers in developing countries by large multinational corporations.
An international panel of speakers trace the progress of human genetics from its beginning to the present day, in various communities in different countries. Both fundamental advances and national developments are reviewed by scientists and historians from the USA, UK, France, Hungary, Japan, India, Russia, etc. Topics include: the development of the research and teaching of human genetics; of the technologies for screening, diagnosis, prediction, prevention and treatment of hereditary diseases; the distribution of these diseases in different communities and different countries; the pioneers and prominent figures in the field and their achievements.
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