X-Ray Crystallography of Biomacromolecules —— A Practical Guide

----- 生物大分子X射线结晶学实用手册：原理与应用

ISBN: 9783527313969 出版年：2007 页码：321 Albrecht Messerschmidt Wiley

Written by one of the most significant contributors to the progress of protein crystallography, this practical guide contains case studies, a troubleshooting section and pointers on data interpretation. It covers the theory, practice and latest achievements in x-ray crystallography, such that any researcher in structural biology will benefit from this extremely clearly written book. Part A covers the theoretical basis and such experimental techniques as principles of x-ray diffraction, solutions for the phase problem and time-resolved x-ray crystallography. Part B includes case studies for different kinds of x-ray crystal structure determination, such as the MIRAS and MAD techniques, molecular replacement, and the difference Fourier technique.