New Insights into GnRH Neuron Development, Programming and Regulation in Health and Disease —— Special Topic Issue: Neuroendocrinology 2015, Vol. 102, No. 3

----- GnRH神经元在健康和疾病中的发展、编程和调控的新见解

ISBN: 9783318056938 出版年：2015 页码：80 S.Karger

This special issue of Neuroendocrinology brings together a series of new aspects in GnRH research, encompassing fundamental studies on the regulation of the GnRH neuron at a molecular and electrophysiological level, studies on pulsatile gene expression in GnRH-promoter-luciferase transgenic mice, and the impact of novel guidance proteins (semaphorins) on GnRH neuron migration. Further topics include animal models of metabolic, immunological, bacterial and steroidogenic reproductive neuroendocrine programming, and clinical studies on the use of kisspeptin ligands to stimulate or inhibit the reproductive system. The discoveries and proposals made in this issue promise to revolutionize the current understanding of the mechanism of GnRH neuron regulation of reproduction, and will be essential reading for anyone involved in the field of GnRH research.