Part 1 Physiological roles of protease: participation of lysosomal cathepsins in antigen processing and bone resorption, N. Katunuma the refined X-ray crystal structures of human and rat liver cathepsin B, W. Bode et al a novel calpain species, n-calpain, active at nM levels of calcium?, H. Sorimachi and K. Suzuki human cysteine proteinases and their inhibitors, stefins and cystatins, V. Turk and W. Bode molecular recognition of proteases associated with cascade reactions, M. Sasaki and I. Ohkubo the expression and structure of rat cystatin beta gene, N. Sato et al meprins and other members of the "Astacin Family" of metalloendopeptidases, W. Jiang and J.S. Bond biosynthesis, processing, and localization of cathepsin E, K. Yamamoto et al proteasome and ubiquitin-dependent proteolysis, K. Tanaka and A. Ichihara turnover of heat-shock proteins, H. Holzer et al. Part 2 Pathogenesis and protease: alterations in processing and trafficking of cathepsin B during malignant progression, B.F. Sloane et al viral proteases - a personal odyssey, B.D. Korant proteolysis-induced pathomechanisms in acute inflammation and related therapeutic approaches, M. Jochum et al neutral proteases of human mast cells, L.B. Schwartz a processing protease for gp 160 HIV-1 envelope glyco-protein precursor in human T4+ lymphocytes, H. Kido et al fibrinogen - a plasma protein of many functions, E.W. Davie et al mechanisms for alteration of the proteinase-proteinase inhibitor balance in tissues, J. Travis snake venom haemorrhagic and non-haemorrhagic metalloproteinases - their structure and function relationships, H. Takeya and S. Iwanaga inactivation and fragmentation of alpha 1-protease inhibitor by Cu, Zn-superoxide dismutase and hydrogen peroxide via liberation of hydroxyl radical, H. Maeda et al.
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