Cisplatin: Pharmacology, Clinical Uses and Adverse Effects

ISBN: 9781619423619 出版年：2012 页码：193 Toshiko Kojima Yoko Morita Nova Science

Cisplatin is a platinum-based anticancer drug and widely used for the treatment of human testicular, ovarian, bladder, cervical, head and neck, and small cell lung cancers. Its anticancer activity results from the modification of DNA through covalent cross-linkings or platinum (Pt)-DNA adducts. This book presents topical research in the study of the pharmacology, clinical uses and adverse effects of cisplatin therapy.