Bioinformatics —— A Practical Approach

----- 生物信息学

ISBN: 9780367388751 出版年:2007 页码:646 CRC Press

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内容简介

Genome and DNA Sequence Analysis Genome Analysis Genome structure analysis by genome browser Sequence similarity searching by BLAST Two Common DNA Analysis Tools Restriction mapping PCR application Phylogenetics Analysis Multiple sequence alignments Building phylogenetics tree SNP and Haplotype Analysis SNP analysis Haplotype analysis Transcriptome and RNA Sequence Analysis Gene Expression Profiling by Microarray Experimental design Data acquisition and preprocessing Data analysis Tutorial Gene Expression Profiling by SAGE SAGE experimentation SAGE data analysis Retrieve data from SAGE database Regulation of Gene Expression Alternative promoters Alternatively splicing Alternative translation initiation RNA editing MicroRNoma Genome-Wide Profiling by Microarray What are miRNAs? microRNAs and human diseases Significance of microRNA profiling Significance of microRNA CGH assay Genome-wide microRNA profiling by microarray RNAi Introduction of RNAi and siRNA Search for siRNA information Proteome and Protein Sequence Analysis Proteome Analysis Analyzing 2DE-derived data Analyzing mass spectrometry derived data Analyzing data derived from protein microarrays Protein Sequence Analysis Primary structure analysis Secondary and tertiary structure analysis Pattern and profile search Protein Function Analysis Protein function annotation Protein posttranslational modifications Protein-protein interactions Functional Annotation of Proteins in Murine Models Various murine models of human diseases Search for murine databases Basic Biocomputing Tools Application of Programming Languages in Biology Application of Perl in biology Application of R in biology Website and Database Design Personal website design Nuts and bolts of biological databases and their constructions Microsoft Excel and Access Microsoft Excel Microsoft Access Interchange data between Microsoft Excel and Access Appendices Abbreviations Selected glossary Websites for selected bioinformatics softwares Index

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