Techniques in Epidermal Biology: An Integrated Approach to Autoimmune Skin Disease

ISBN: 9781612096216 出版年：2011 页码：190 Nicola Cirillo Nova Science

The high-throughput techniques underlying a systems level analysis of biological organisms have emerged as powerful tools in the study of disease mechanisms. On the other hand, they require substantial funding and multidisciplinary skills. Therefore, basic biochemical/cell biology methods from molecular bioscience are still needed to address key biological questions. This new book uses the autoimmune disease Pemphigus Vulgaris (PV) as an experimental model of epidermal disease. Simple molecular bioscience principles and high-throughput methods to clarify disease pathophysiology are presented, which lead to novel therapeutic modalities.