Ubiquitin Ligase: New Insights, Emerging Roles and Clinical Implications

ISBN: 9781536109122 出版年：2017 页码：219 Edward T Harris Nova Science

The E3 ubiquitin ligases facilitate substrate specificity and isopeptide bond formation between C-terminal glycine residue of ubiquitin (Gly 76) and a lysine residue in the target protein. This book reviews several new insights, discusses emerging roles and analyzes clinical implications of uniquitin ligases.