Neurofibromatosis (NF): Diagnosis, Management and Health Impact

ISBN: 9781536107050 出版年：2017 页码：120 Jeremy Murphy Nova Science

Neurofibromatosis 1 (NF1) is a neurocutaneous disorder with a heterogenous presentation affecting 1 in 2500 to 1 in 3000 births. Our understanding of the pathogenesis of NF1 has increased dramatically since the discovery of the NF1 gene in 1990 and the role its product, neurofibromin, plays in tumor suppression. This book provides new research on the diagnosis, management and health impacts of NF.