TNF Superfamily

ISBN: 9781587063060 出版年：2007 页码：109 Khare, Sanjay V CRC Press

The tumor necrosis factor/receptor [TNF/TNFR] superfamily consists of more than 20 transmembrane proteins with conserved N-terminal cysteine-rich domains [CRDs] in the extracellular ligand binding region. Members have wide tissue distribution and play important roles in biological processes such as lymphoid and neuronal development, innate and adap