Leptin and Leptin Antagonists

ISBN: 9781587063206 出版年：2009 页码：184 Gertler, Prof Arieh CRC Press

The discovery of leptin, the obese (ob) gene product which is not expressed as a functional protein in ob/ob mice, focused the scientific community's attention on its role as an anorexic hormone involved in the negative regulation of food intake. Almost 14 years after this breakthrough discovery and over 14,000 leptin-related publications later, le