Molecular Mechanisms of Ataxia Telangiectasia

ISBN: 9781587063220 出版年：2009 页码：133 Ahmad, Shamim I CRC Press

Ataxia telangiectasia (AT) is an incurable, rare autosomal recessive genetic disorder which affects approximately one in 40,000-100,000 and the carrier frequency is estimated to be 1:100-200. In the United Kingdom it affects 1 in 300,000 live births amounting to about 5 or 6 cases per year. Although the medial survival rate of affected persons is b