Growth Hormone Secretagogues in Clinical Practice

ISBN: 9780367400484 出版年：1998 页码：463 Bercu, Barry B Walker, Richard F CRC Press

Part 1 Scope of non-GHRH growth hormone secretagogues: synergistic release of growth hormone by GHRP and GHRH - scope and implication structural requirements of growth hormone secretagogues unifying mechanism of non-GHRH growth hormonesecretagogues's action molecular cloning and characterization of human, swine and rat growth hormone secretagogues receptors a mathematical model for growth hormone release from the pituitary evidence for a new subtype of GHRP receptors in ovinepituitary gland. Part 2 Experimental pharmacology: agonists analogs of growth hormone-releasing hormone - endocrine and growth studies antagonistic analogs of growth hormone-releasing hormone - endocrine and oncological studies clinical evidence forextrahypophyseal site of growth hormone secretagogues electrophysiological studies of the arcuate nucleus - central actions of growth hormone secretagogues effects of a growth hormone-releasing peptide-like nonpeptidyl growth hormone secretagogue onphysiology and function on aged rats anterior pituitary function in prolonged critical illness - effects of continuous infusion of growth hormone secretagogues hepatic extraction of hexarelin, a new peptide growth hormone secretagogue, in the isolatedperfused rat liver the effect of growth hormone secretagogues on the release of growth hormone-releasing hormone, somatostatin, vasopressin and corticotrophin-releasing hormone from the rat hypothalamus in vitro immunocytochemical studies investigatingthe central actions of the nonpeptidyl growth hormone secretagogue, MK-0677. Part 3 Clinical applications of growth hormone secretagogues: evaluation of pituitary function using growth hormone secretagogues clinical use of growth hormone secretagogues short- and long-term growth hormone secretagogue administration in children endocrine response to growth hormone-releasing peptides across human life span GHRH and GHRP-5 exert different effects on sleep electroencephalograms and nocturnal hormonesecretion in normal men. (Part contents).