Solid-Phase Synthesis —— A Practical Guide

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ISBN: 9780367398712 出版年：2000 页码：849 CRC Press

The solid support strategy in solid-phase synthesis amino acids -alpha-amino protecting groups side-chain protecting groups solid supports for the synthesis of peptides and small molecules coupling methods - solid-phase formation of amide and ester bonds homodetic cyclic peptides disulfide formation in synthetic peptides and proteins -the state of the art solid-phase convergent approaches to the synthesis of native peptides and proteins preparation of glyco-, phospho-, and sulfopeptides oligonucleotide synthesis synthesis of oligonucleotide-peptide conjugates and nucleopeptides the chemistry of peptide nucleic acids solid-phase synthesis of pseudopeptides and oligomeric peptide backbone mimetics instrumentation the purification of synthetic peptides analysis of synthetic peptides the chromatographic analysis of combinational arrays - parallel HPLC and HPLC-MS.