Applied Surrogate Endpoint Evaluation Methods with SAS and R

ISBN: 9781482249361 出版年：2016 页码：396 Alonso, Ariel Bigirumurame, Theophile Burzykowski, Tomasz CRC Press

An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.