Computer Techniques in Preclinical and Clinical Drug Development

ISBN: 9780367401283 出版年：1996 页码：873 Jackson, Robert C CRC Press

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational method