Biocatalysis in the Pharmaceutical and Biotechnology Industries

ISBN: 9780367446284 出版年：2006 页码：878 CRC Press

Nitrilases and Nitrile Hydratases R. DiCosimo Biocatalytic Deracemization: Dynamic Resolution, Stereoinversion, Enantioconvergent Processes and Cyclic Deracemization Y.Simeo, W. Kroutil, and K. Faber A Decade of Biocatalysis at Glaxo Wellcome M. Mahmoudian Biocatalysis for Synthesis of Chiral Pharmaceutical Intermediates R.N. Patel Directed Evolution of Lipases and Esterases for Organic Synthesis A. Hidalgo and U.T. Bornscheuer Flavin-Containing Oxidative Biocatalysts M.W. Fraaije and W.J.H. van Berkel Preparation of Chiral Pharmaceuticals through Enzymatic Acylation of Alcohols Amines V. Gotor-Fernandez, F. Rebollledo, and V. Gotor Dynamic Kinetic Resolution and Asymmetric Transformations by Enzyme-Metal Combinations M.J. Kim, Y. Ahn, and J. Park Biotransformation of Natural or Synthetic Compounds for the Generation of Molecular Diversity R. Azerad Applications of Aromatic Hydrocarbon Dioxygenases R.E. Parales and S.M. Resnick A Genomic Approach to Investigating Baker's Yeast Reductions J.D. Stewart Immobilization of Enzymes as Cross-linked Enzyme Aggregates: A Simple Method for Improving Performance R.A. Sheldon Biotechnological Applications of Aldolases W.D. Fessner and S.Jennewein Enzymatic Synthesis of Modified Nucleosides L.A. Condezo, J. Fernandez-Lucas, C.A. Garcia-Burgos, A.R. Alcantara, and J.V. Sinisterra Biocatalytic Reduction of Carboxylic Acids: Mechanism and Applications P. Venkitasubramanian, L. Daniels, and J.P.N. Rosazza Dehalogenases in Biodegradation and Biocatalysis D.B. Janssen Enzymatic Synthesis of Sugar Esters and Oligosaccharides from Renewable Resources A. Ballesteros, F.J. Plou, M. Alcalde, M. Ferrer, H. Garcia-Arellano, D. Reyes-Duarte, and I. Ghazi Efficient Methods and Instrumentation for Engineering Custom Enzymes S.J. Robles, W.J. Coleman, and M.M. Yang Deaminating Enzymes of the Purine Cycle as Biocatalysts for Chemoenzymatic Synthesis and Transformation of Antiviral Agents Structurally Related to Purine Nucleosides E. Santaniello, P. Ciuffreda, and L. Alessandrini Microbial and Enzymatic Processes for the Production of Chiral Compounds K. Honda, T. Ishige, and S. Shimizu Discovery of Arylmalonate Decarboxylase and Conversion of the Function by Rational Design K. Miyamoto and H. Ohta Chemoenzymatic Preparation of Enantiopure Building Blocks of Synthetic Utility K. Mori Stereoselective Modifications of Polyhydroxylated Steroids E. Fossati and S. Riva Recent Developments in Enzymatic Acyloin Condensations O. Ward and A. Singh Synthesis of Chiral Alcohols with Carbonyl Reductase Library and Robust NAD(P)H Regenerating System H. Yamamoto and A. Matsuyama Comparative Analysis of Chemical and Biocatalytic Syntheses of Drug Intermediates M.J. Homann, W.C. Suen, N. Zhang, and A. Zaks Industrial Processes Using Lyases for C-C, C-N, and C-O Bond Formation M. Pohl and A. Liese State of the Art and Applications in Stereoselective Synthesis of Chiral Cyanohydrins F. Effenberger, S. Forster, and C. Kobler Chiral Switches: Problems, Strategies, Opportunities, and Experiences R. Csuk Enzyme Evolution for Chemical Process Applications G.W. Huisman and J.J. Lalonde Biocatalytic Routes to Nonracemic Chiral Amines N.J. Turner and R. Carr Enantioselective Biocatalytic Reduction of Ketones for the Synthesis of Optically Active Alcohols S. Buchholz and H. Groger Enzyme Catalysis in Nonaqueous Media: Past, Present, and Future S. Dreyer, J. Lembrecht, J. Schumacher, and U. Kragl Biocatalytic Concepts for the Synthesis of Optically Active Amines S. Buchholz and H. Groger Index