Receptor - Based Drug Design

ISBN: 9780367400521 出版年：1998 页码：401 CRC Press

Introduction, James Black Principles and Measurement of Drug-Receptor Interactions The Characterization and Classification of Receptors, Patrick P. A. Humphrey Functional Methods for Quantifying Agonists and Antagonists, Iain G. Dougall Quantification of Receptor Interactions Using Binding Methods, Sebastian Lazareno Drug Analysis Based on Signaling Responses to G-Protein-Coupled Receptors, T. Kendall Harden, Jose L. Boyer, and Robert W. Dougherty The Use of Electrophysiology to Improve Understanding of Drug-Receptor Interactions, John G. Connolly and Charles Kennedy Receptor-Based Drugs in Medicine Selective Adrenergic and Glucocorticoid Treatments for Asthma, David Jack Serotonin 5-HT1B/D Receptor Agonists, Graeme R. Martin Histamine H2-Receptor Antagonists, Michael E. Parsons Angiotensin Antagonists, Mark J. Robertson Experimental and Emerging Drugs -Adrenoceptor Agonists and Antagonists, J. Paul Hieble and Robert R. Ruffolo, Jr. P2U-Purinoceptor Agonists: Emerging Therapy for Pulmonary Diseases, Eduardo R. Lazarowski, William C. Watt, T. Kendall Harden, and Richard C. Boucher Muscarinic Receptor Antagonists Pharmacological and Therapeutic Utility, Richard M. Eglen NMDA Receptor Antagonists, John A. Kemp and James N. C. Kew New Trends in Drug Design Computational Chemistry in Receptor-Based Drug Design, Ad P. IJzerman, Eleonora M. van der Wenden, and Wilma Kuipers Recombinant G-Protein-Coupled Receptors as Screening Tools for Drug Discovery, A. Donny Strosberg and Prabhavathi B. Fernandes Inverse Agonists and G-Protein-Coupled Receptors, Richard A. Bond and Michel Bouvier