Chemistry and Biology of Synthetic Retinoids

ISBN: 9781315891538 出版年：2018 页码：628 Dawson, Marcia I CRC Press

The Bioorganic Chemistry of Vision (Robert R. Rando). The Molecular Basis of the Visual Cycle (C.D.B. Bridges). The Binding Site of Opsin Based on Analog Studies with Isomeric, Fluorinated, Alkylated, and Other Modified Retinals (Robert S.H. Liu and Alfred E. Asato.). Synthesis and Application of Retinoids and Related Compounds to Vision Research and Cancer Studies (Mayayoshi Ito). Molecular Mechanism for the Function of Bacteriorhodopsin and Visual Pigments: Studies with Model Compounds and Artificial Pigments (Mordechai Sheves and Michael Ottolenghi). Analog Pigments of Rhodopsin and Bacteriorhodopsin Retinal-Binding Site and Role of the Chromophore in the Functionality of the Pigments (Rosalie K. Crouch). Visual Pigment and Bacteriorhodopsin Analogs (Valeria Balogh-Nair and Koji Nakanishi). Acetylenic Intermediates in Retinoid Synthesis (Henning Hopfand Norbert Krause). Synthesis and Studies of 12-s-cis Conformationally Locked Retinoids (Angel R. de Lera Roshantha A.S. Cha ndraratna and William H. Okamura.). Is Retinoic Acid a Physiologically Significant Promoter of Differentiation? (Joseph L. Napoli). Inhibition of Melanoma Growth by Retinoids: Structure-Activity Relationships (Reuben Lotan and Dafna Lotan). Structure-Activity Relationships of a New Series of Synthetic Retinoids (Retinobenzoic Acids) (Koichi Shudo and Hiroyuki Kagechika). Regulation of Squamous Differentiation in Tracheobronchial Epithelial Cells by Synthetic Retinoids (Anton M. Jetten). Structure-Biological Activity Relationships of New Synthetic Retinoids on Epithelial Differentiation of Cultured Hamster Trachea (Leonard J. Schiff William H. Okamura Marcia I. Dawson and Peter D. Hobbs). Cellular Retinoic Acid-Binding Protein and the Action of Retinoic Acid (Brahma P. Sani). The Inhibitory Effects of Retinoids on the Induction of Ornithine Decarboxylase and the Promotion of Tumors in Mouse Epidermis (Marcia I. Dawson Wan-Ru Chao Peter D. Hobbs and Thierry Delair). Role o f Retinoids in Prevention of Cutaneous Cancer (Helen L. Gensler and Frank L. Meyskens, Jr.). Epidermal Responses to Retinoids In Vivo (Michael J. Connor). Retinoid Inhibition of Experimental Carcinogenesis (Richard C. Moon and Rajendra G. Mehta.). Retinoids as Potential Antirheumatic Agents (John W. Coffey Christa Fiedler-Nagy Stephen M. Weisman Thasis G. Woodworth and Ann F. Welton). Molecular Correlates in Retinoid Pharmacology and Toxicology (Calvin C. Willhite). Carcinogenesis Inhibitory Properties of Retinoids: A QSAR-MTD Analysis (I. Niculescu-Duvaz Z. Simon and N. Voiculetz). c. 560 pp., 7x10, 1989, ISBN-0-8493-4797-1. Features: