Applications of Transition Metal Catalysis in Drug Discovery and Development —— An Industrial Perspective

----- 药物发现与开发的过渡金属催化应用：工业展望

ISBN: 9780470631324 出版年：2012 页码：376 Matthew L Crawley Barry M Trost Wiley

This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs.  The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.