Zebrafish —— Methods for Assessing Drug Safety and Toxicity

----- 斑马鱼：药物安全性和毒性评估方法

ISBN: 9780470425138 出版年：2011 页码：362 Patricia McGrath Wiley

Offering a broad range of methods, Zebrafish explains how to assess compound-induced toxicity in all major organs using the zebrafish as a model organism. The authors effectively demonstrate why this vertebrate model offers compelling experimental advantages, including drug delivery directly in the fish water, small quantity of drug required per experiment, statistically significant number of animals per test, and low cost. Moreover, the authors describe how drug assessment can be performed using wild-type, mutant, transgenic, and knock-down zebrafish models.