Pharmacogenetics of Psychotropic Drugs

ISBN: 9780521189613 出版年：2002 页码：460 Lerer Cambridge University Press

Part I. Introduction: 1. Genes and psychopharmacology: exploring the interface Bernard Lerer Part II. Clinical Background and Research Design: 2. From pharmacogenetics to pharmacogenomics of psychotropic drug response Anil K. Malhotra 3. Neuropsychopharmacology: the interface between genes and psychiatric nosology Thomas A. Ban 4. Methodological issues in psychopharmacogenetics Sheldon H. Preskorn 5. Statistical approaches in psychopharmacogenetics Fabio Macciardi Part III. Molecular Background: 6. The psychopharmacogenetic-neurodevelopmental interface in serotonergic gene pathways K. Peter Lesch, Jens Benninghoff and Angelika Schmitt 7. RNA processing regulation and interindividual variation Colleen M. Niswender and Linda K. Hutchinson Part IV. Pharmacokinetics: 8. Pharmacogenetics of psychotropic drug metabolism Vural Ozdemir, Angela D. M. Kashuba, Vincenzo S. Basile and James L . Kennedy 9. Pharmacogenetics of chiral psychotropic drugs Pierre Baumann and Chin B. Eap Part V. Specific Psychotropic Drugs and Disorders: 10. Clozapine response and genetic variation in neurotransmitter receptor targets David A. Collier, Maria J. Arranz, Sarah Osborne, Katherine J. Aitchison, Janet Munro, Dalu Mancama and Robert W. Kerwin 11. Genetic factors underlying drug-induced tardive dyskinesia Ronnen H. Segman and Bernard Lerer 12. Functional gene-linked polymorphic regions in pharmacogenetics Marco Catalano 13. Alternative phenotypes and the pharmacogenetics of mood and anxiety disorders Emanuela Mundo and James L. Kennedy 14. Pharmacogenetics of anxiolytic drugs and the GABA-benzodiazepine receptor complex Smita A. Pandit, Spilios V. Argyropoulous, Patrick G. Kehoe and David J. Nutt 15. Genetic factors and long-term prophylaxis in bipolar disorder Martin Alda 16. Genetic influences on responsiveness to anticonvulsant drugs Thomas N. Ferraro 17. Apolipoprotein E as a marker in the treatment of Alzheimer's disease Keith Schappert, Pierre Sevigny and Judes Poirier 18. Genetic variation and drug dependence risk factors Joel Gelernter and Henry Kranzler Part VI. Pharmacogenetics and Brain Imaging: 19. Brain imaging and pharmacogenetics in Alzheimer's disease and schizophrenia Steven G. Potkin, James L. Kennedy and Vincenzo S. Basile Part VII. Industry perspectives: 20. Pharmacogenetics in psychotropic drug discovery and development William Z. Potter, AnnCatherine Van Lone and Larry Altstiel 21. High-throughput single nucleotide polymorphism genotyping Anne Shalom and Ariel Darvasi Index.