Comparative Pharmacokinetics —— Principles, Techniques and Applications

----- 比较药代动力学

ISBN: 9780813821382 出版年：2011 页码： Jim E Riviere Wiley

Introduction principles of drug movement in the body absorption distribution renal elimination hepatic biotransformation and biliary excretion compartmental models noncompartmental models nonlinear models physiological models dosage regimens simultaneous pharmacokinetics-pharmacodynamics modelling study design and data analysis population pharmacokinetics models and Bayesian forecasting applied to clinical pharmacokinetics dosage adjustment in renal diseases interspecies extrapolations tissue residues and withdrawal times.