Automation in Proteomics and Genomics —— An Engineering Case-Based Approach

----- 蛋白质组学与基因组学的自动化：基于工程实例的研究

ISBN: 9780470727232 出版年：2009 页码：341 Gil Alterovitz Roseann M Benson Wiley

Preface. List of Contributors. About the Editors. SECTION 1 FUNDAMENTALS OF MOLECULAR AND CELLULAR BIOLOGY 1 The Central Dogma: From DNA to RNA, and to Protein ( Takashi Ohtsuki, Masahiko Sisido). 2 Genomes to Proteomes ( Ellen A. Panisko, Igor Grigoriev, Don S. Daly, Bobbie-Jo Webb-Robertson and Scott E. Baker). SECTION 2 ANALYSIS VIA AUTOMATION. 3 High-Throughput DNA Sequencing ( Tarjei S. Mikkelsen). 4 Modeling a Regulatory Network Using Temporal Gene Expression Data: Why and How ( Sophie L'ebre and Gaelle Lelandais)? 5 Automated Prediction of Protein Attributes and Its Impact on Biomedicine and Drug Discovery ( Kuo-Chen Chou). 6 Molecular Interaction Networks: Topological and Functional Characterizations ( Xiaogang Wu and Jake Y. Chen). SECTION 3 DESIGN VIA AUTOMATION. 7 DNA Synthesis ( Jingdong Tian). 8 Computational and Experimental RNA Nanoparticle Design ( Isil Severcan, Cody Geary, Luc Jaeger, Eckart Bindewald, Wojciech Kasprzak and Bruce A. Shapiro). 9 New Paradigms in Droplet-Based Microfluidics and DNA Amplification ( Michael L. Samuels, John Leamon, Jonathan Rothberg, Ronald Godiska, Thomas Schoenfeld and David Mead). 10 Synthetic Networks ( Jongmin Kim). SECTION 4 INTEGRATION. 11 Molecular Modeling of CYP Proteins and its Implication for Personal Drug Design ( Jing-Fang Wang, Cheng-Cheng Zhang, Jing-Yi Yan, Kuo-Chen Chou and Dong-Qing Wei). 12 Recent Progress of Bioinformatics in Membrane Protein Structural Studies ( Hong-Bin Shen, Jun-Feng Wang, Li-Xiu Yao, Jie Yang and Kuo-Chen Chou). 13 Trends in Automation for Genomics and Proteomics ( Gil Alterovitz, Roseann Benson, Marco Ramoni and Dmitriy Sonkin). Index.