Emerging Nanotechnologies in Immunology —— The Design, Applications and Toxicology of Nanopharmaceuticals and Nanovaccines

----- 免疫学中新兴纳米技术的应用：纳米药物和纳米抗菌素的设计、应用和毒理学

ISBN: 9780323400169 出版年：2018 页码：291 Elsevier Science_RM

Emerging Nanotechnologies in Immunology aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanophamaceuticals currently in the pipeline of S&T development for skin, ocular, and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure. The scientific development of manufactured nanomaterials for drug delivery is increasing rapidly. One of the most prominent applications is topical drug delivery, where cutaneous, ocular, and nasal exposure becomes even more relevant. These targets are the first barrier that nanoparticles encounter when in contact with the human body. The contributors addresses a representative set of the broad spectrum of nanopharmaceuticals currently being used, including cationic lipid nanoparticles, polymeric PLGA, PLA nanoparticles, biomacromolecules-based nanoparticles, and other scaffolds tissue engineered skin substitutes. Regulation and risk is also covered, since the safety of these nanophamaceuticals still represents a barrier to their wide innovative use.Provides the reader with a thorough knowledge of the safety aspects of nanopharmaceuticals which are currently under researchFocuses on the characterization and quantification of the nanopharmaceuticalsAllows readers to understand the correlation between the nature of the materials and their potential nanotoxicological effects.Includes an overview of regulatory aspects related to the R&D of nanopharmaceuticals.