DNA Methylation —— Approaches, Methods, and Applications

----- 脱氧核糖核酸的甲基化

ISBN: 9780849320507 出版年：2004 页码：240 CRC Press

Describing the relation DNA methylation has to gene silencing in disease, this book explores its promising role in treating cancer. Written by leaders in the field, it outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. Including concepts, experimental models, and clinical uses of demethylating agents, the book provides articles clarifying methodological details and more general review chapters that offer broad biological perspectives on DNA methylation. This is an invaluable handbook for researchers and clinicians interested in genetics and molecular biology, particularly epigenetic therapies and gene silencing.