Mental Retardation and Developmental Delay —— Genetic and Epigenetic Factors

----- 智力迟钝和发育迟缓:遗传和表观遗传因素.

ISBN: 9780195174328 出版年：2005 页码：338 Smith, Moyra M D Oxford University Press

This book makes readily available current knowledge on the subject of mental retardation and developmental delay and applies it to clinical medicine, providing information essential to neurologists, geneticists, physicians and pediatricians as they search for the causes of mental handicap in their patients. Chapters cover normal and abnormal brain structure, neurogenesis, and signal transduction before delving into a discussion of both the environmental factors that may lead to neurocognitive deficits and the cytogenetic, biochemical and molecular defects specifically associated with mental retardation. The text concludes with a clinically practical discussion of carrier detection, presymptomatic diagnosis, and treatment of various genetic diseases.