Essentials of Noncoding RNA in Neuroscience —— Ontogenetics, Plasticity of the Vertebrate Brain

----- 在神经科学中的非编码RNA的要领：遗传学、脊椎动物的大脑的可塑性

ISBN: 9780128044025 出版年：2017 页码：340 Academic Press_RM

Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in complex processes. It is of strong interest to those working to develop enabling technologies to detect and monitor miRNA expression and function, and to evaluate its roles in neural progenitor proliferation/differentiation, neuronal plasticity, and learning and memory.Discusses the unique features of neural miRNAsDetails functional investigation of miRNA actions and current experimental approachesIncludes extensive coverage of miRNA biology, developmental and postnatal neurogenesis, and computational challenges for miRNA target identificationContains thorough discussion of the transcriptional control of miRNA expression in forebrain development and in specific neuronal subtypes, as well as miRNA function in neurogenesis, neuronal network maturation, plasticity, gliogenesis, and dysfunctionProvides an overview of miRNA roles in neurodevelopmental disorders and their possible role in the evolution of the neocortex