Recent Trends in Carbohydrate Chemistry —— Synthesis and Biomedical Applications of Glycans and Glycoconjugates

----- 糖类和糖缀合物的碳水化合物化学合成和生物医学应用的最新趋势

ISBN: 9780128209547 出版年：2020 页码：440 Elsevier Science_RM

Recent Trends in Carbohydrate Chemistry: Synthesis and Biomedical Applications of Glycans and Glycoconjugates covers biomedically relevant bacterial cell wall carbohydrates including recent findings on biosynthetic aspects, advances in the chemical assembly of bacterial lipopolysaccharide fragments and teichoic acids, and modern NMR approaches to unravel structural details. The first part introduces and provides the relevant background for synthetic glycoconjugate vaccines. The second section focuses on synthetic carbohydrate-based vaccines of therapeutic potential that are licensed or under development. This second volume of Recent Trends in Carbohydrate Chemistry is ideal for researchers working as synthetic organic chemists, as well as those interested in glycoconjugation, protein chemists, immunologists, and microbiologists, in academia as well as in industry.Highlights important features of bacterial glycoproteinsIllustrates modern chemical synthesis and structural analysis of bacterial glycansDemonstrates the importance of carbohydrate chemistry for the synthesis of lipopolysaccharides and teichoic acidCovers recent findings on glycan ligationGives an overview of the most recent developments on carbohydrate-based vaccines