Developmental and Fetal Origins of Differences in Monozygotic Twins —— From Genetics to Environmental Factors

----- 单卵双胞胎的差异发育和胎儿起源：从遗传到环境因素

ISBN: 9780128200476 出版年：2020 页码：387 Academic Press_RM

Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout.Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical managementDiscusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysisFeatures contributions from international experts in twin genetics and developmental biology