From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors

ISBN: 9780128201879 出版年：2020 页码：330 Academic Press_Series

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo鈥恠witchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP鈥? receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure鈥恇ased discovery and development of mGlu5 NAMs, and much more. Includes the authority and expertise of leading contributors in pharmacologyPresents the latest release in the Advances in Pharmacology series