Gene Environment Interactions —— Nature and Nurture in the Twenty-first Century

----- 基因与环境的相互作用:21世纪的先天与后天

ISBN: 9780128196137 出版年：2020 页码：426 Smith, Moyra Academic Press_RM

Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome intrinsic effects on human health, and the gene-environment etiology of cardiovascular, metabolic, psychiatric, behavioral and monogenic disorders. Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition, the book's author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population.Offers a thorough, interdisciplinary discussion on recent revelations from gene environment interaction studiesIlluminates environmental factors affecting disease-gene etiology and treatmentSupports the clinical translation of gene environment interaction findings into novel therapeutics and precision medicine