Cancer-Leading Proteases —— Structures, Functions, and Inhibition

----- 致癌蛋白酶:结构、功能和抑制

ISBN: 9780128181683 出版年：2020 页码：526 Academic Press_RM

Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases. Explains the role of proteases in the biology of cancerDiscusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkersCovers a wide range of cancers and provides detailed discussions on protease examples