Protein Interactions as Targets in Drug Discovery

ISBN: 9780128168462 出版年：2020 页码：318 Academic Press_Series

Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interactions. Chapters in this new release include Trends in structure based drug design with protein targets, From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD), Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis, Aromatic-aromatic interactions in protein-drug and protein-protein interactions, Role of protein-protein interaction in allosteric drug design within the human methyltransferome, and much more.Integrates experimental and computational methods for studying protein interactions and their modulation by potential therapeuticsContains timely chapters written by well-renown authorities in their fieldCovers information that is well supported by a number of high quality illustrations, figures and tablesTargets a very wide audience of specialists, researchers and students