Genetics and Genomics of Eye Disease —— Advancing to Precision Medicine

----- 眼病的遗传学和基因组学：推进精准医学

ISBN: 9780128162224 出版年：2019 页码：386 Academic Press_RM

Genetics and Genomics of Eye Disease: Advancing to Precision Medicine thoroughly examines the latest genomics methods for studying eye disease, including complex eye disorders associated with multiple genes. GWAS, WES, WGS, RNA-sequencing, and transcriptome analysis as employed in ocular genomics are discussed in-depth, as are genomics findings tied to early-onset glaucoma, strabismus, age-related macular degeneration, adult-onset glaucoma, diabetic retinopathy, keratoconus, and leber congenital amaurosis, among other diseases. Research and clinical specialists offer guidance on conducting preventative screenings and counseling patients, as well as the promise of machine learning, computational statistics and artificial intelligence in advancing ocular genomics research.Offers thorough guidance on conducting genetic and genomic studies of eye diseaseExamines the genetic basis of a wide range of complex eye diseases and single-gene and Mendelian disordersDiscusses the application of genetic testing and genetic risk prediction in eye disease diagnosis and patient counseling