DNA Repair

ISBN: 9780128155592 出版年：2019 页码：386 Academic Press_Series

DNA Repair, Volume 115, the latest release in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more. Describes advances in our understanding on DNA repair mechanisms and the involvement of their dysregulation in promoting diseasesPresents data that is targeted to a very wide audience of specialists, researchers and studentsContains timely chapters written by well-renowned authorities in their fieldProvides targeted information that is well supported by a number of high-quality illustrations, figures and tables