Diagnostic and Therapeutic Applications of Exosomes in Cancer

ISBN: 9780128127742 出版年：2018 页码：402 Academic Press_RM

Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer. Covers emerging pharmaceutical and diagnostic applications, including exosomes being tested as carriers of anticancer drugs, ongoing clinical trials, and exosomes as imaging agents for cancer diagnosis and treatmentBrings together a team of highly regarded international authors who provide a full-rounded analysisPresents comprehensive coverage of the unique biophysical properties of exosomesExplores current and future possibilities