The End of Alzheimer —— The Brain and Beyond

----- 阿尔茨海默病的终结：大脑和其他

ISBN: 9780128121122 出版年：2017 页码：484 Lewis, Thomas J Trempe, Clement L Academic Press_RM

The End of Alzheimer: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer outside the brain and argues that a more thorough, whole-body diagnosis will provide better answers about its causes and lead to new treatments. It is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer, and will hopefully redirect many into new avenues of cellular research and discovery. Comprehensive literature-based summary of the current state of molecular Alzheimer disease researchDetails the shortcomings of the prevailing model and therapeutics in developmentReviews blood-based biomarkers for Alzheimer and their link to amyloid- and Tau-independent causes outside the brainDescribes the tissues outside the brain impacted by Alzheimer and the underlying molecular causesExplains the whole-body risks associated with Alzheimer, along with concomitant measures to slow or prevent the diseaseProvides a protocol to properly research, evaluate, measure, diagnose, and potentially treat Alzheimer patients