The Molecular and Clinical Pathology of Neurodegenerative Disease

ISBN: 9780128110690 出版年：2018 页码：276 Lewis, Patrick A Spillane, Jennifer E Academic Press_RM

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration.Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disordersDescribes the clinical background and underlying molecular processes for Alzheimer disease, Parkinson, Prion, Motor Neuron, Huntington, and Multiple SclerosisHighlights the state-of-the-art treatment options for each disorderDetails examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models