Receptors in the Evolution and Development of the Brain —— Matter into Mind

----- 大脑进化与发展中的受体：重要思想

ISBN: 9780128110126 出版年：2019 页码：288 Fine, Richard E Academic Press_RM

Receptors in the Evolution and Development of the Brain: Matter into Mind presents the key role of receptors and their cognate ligands in wiring the mammalian brain from an evolutionary developmental biology perspective. It examines receptor function in the evolution and development of the nervous system in the large vertebrate brain, and discusses rapid eye movement sleep and apoptosis as mechanisms to destroy miswired neurons. Possible links between trophic deficits and connectional diseases including Alzheimer, Parkinson, and ALS are also discussed. This book is extremely useful to those with an interest in the molecular and cellular neurosciences, including those in cognitive and clinical branches of this subject, and anyone interested in how the incredibly complex human brain can build itself.Provides an understanding of the key role receptors play in brain development and the selection process necessary to construct a large brainTraces the evolution of receptors from the most primitive organisms to humansEmphasizes the roles that REM sleep and apoptosis play in this selection via trophic factors and receptorsDescribes the role that trophic factor-receptor interactions play throughout life and how trophic deficits can lead to connectional diseases, including Alzheimer's, Parkinson's and ALSProvides a potential mechanism whereby neuronal stem cells can cure these diseases