Systems Biology in Toxicology and Environmental Health

ISBN: 9780128015643 出版年：2015 页码：285 Academic Press_RM

Systems biology is the integrative study of the interactions of various components of the cell. Understanding the manner in which these components interact, particularly in response to toxic substances in the environment, will facilitate a deeper understanding of biological mechanisms underlying disease. This enhanced understanding is critical for advances in environmental science, toxicology, and clinical medicine. Moreover, the identification of the key components of the systems that mediate cellular responsivity to toxic substances will help to reveal novel targets for disease prevention. The following chapter provides an overview of systems biology including a brief history of the development of this field. A description of the potential integration of systems biology to various disciplines of interest is provided.