Kidney Development, Disease, Repair and Regeneration

ISBN: 9780128001028 出版年：2015 页码：615 Academic Press_RM

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities. Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally. Explains the underlying developmental mechanisms which influence the kidney's inherent repair capacity. Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine.