Organogenesis in Development

ISBN: 9780123809124 出版年：2010 页码：455 Koopman, Peter Academic Press_Series

Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. This volume: summarizes the key morphological and cellular events; emphasizes up-to-date research relating to molecular control mechanisms; draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease; distils common themes and differences for comparative studies; and, highlights key remaining questions and sets the agenda for future research.