The Leukemia-Lymphoma Cell Line Factsbook

ISBN: 9780122219702 出版年：2000 页码：751 Drexler, Hans G Academic Press_RM

The Leukemia-Lymphoma Cell Line Factsbook represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references.The full spectrum of malignant cell lines from all hematopoietic cell lineagesSister cell lines and relevant subclonesClinical data: patient, diagnosis, treatment status, and specimen sourceAuthentication of derivation and availabilityImmunophenotypeCytogenetic karyotypeTranslocations and fusion genesReceptor gene rearrangements and genetic alterationsCell cultures aspects: establishment, medium, doubling time, growthCytochemical profileCytokine production and response to cytokinesProto-oncogene and transcription factor expression/alterationFunctional features: differentiation induction, heterotransplantabilitySpecial unique featuresKey references