The Practice of Medicinal Chemistry

ISBN: 9780127444819 出版年：2003 页码：792 Academic Press_RM

The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process.The only book available dealing with the practical aspects of medicinal chemistryServes as a complete guide to the drug discovery process, from conception of the molecules to drug productionUpdated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry