Bioinformatics

ISBN: 9780444518071 出版年：2006 页码：351 Elsevier Science_RM

The advances in genomic technologies, such as microarrays and high throughput sequencing,have expanded the realm of possibilities for capturing data and analyzing it using automatedcomputer driven bioinformatics tools. With the completion of the sequencing of genomes ofhuman and several model organisms, a quest for scientific discoveries being fueled byintegrative and multidimensional techniques in mathematics and computational sciences. Inthis volume, leading researchers and experts have provided an overview of significantconcepts from biological, mathematical, and computational perspectives. It provides a high level view of fungal genomic data integration and annotation, classification of proteins and identification of vaccine targets, identification of secretome or secreted proteins in fungal genomes, as well as tools for analyzing microarray expressionprofiles. Provides a survey of theoretical underpinnings on the technological tools and applicationsDiscusses the tools utilized for the annotation of fungal genomes and addresses issues related to automated annotation generation in a high throughput biotechnology environmentDescribes the applications of the concepts and methodologies presented throughout the book